Cardiovascular and Respiratory Effects of Romifidine and/or Xylazine in Ketamine Anaesthesia in Dog: An Experimental Study

To compare romifidine and xylazine premedication in ketamine anesthesia ofthe dog.Design: Experimental design.Animals: Fifteen cross-breed dogs.Procedures: Animals randomly allocated into three groups of five. Group G1 premedicatedby xylazine 1 mg/kg, G2 romifidine 40 [g/ kg and G3 romifidine 80 [g/ kgintramuscularly. All animals premedicated with atropine 0.02 mg/kg subcutaneously tenminutes before induction of anesthesia. Anesthesia was induced by 15 mg/kg ketamine IM.Heart rate, respiratory rate, mean arterial blood pressure and eclectrocardiac activity besidequality of anesthesia were evaluated.Results: No significant differences were found between three groups around all recordedparameters.Conclusions and Clinical relevance: Usage of different doses of romifidine in caninespecies is possible without any unexpected outcome, 80 [g/ kg of romifidine make betteronset of anesthesia.