Title of article :
Aqueous solvent as a safe and eco-friendly medium for the clean synthesis of furo[2,3-d]pyrimidines
Author/Authors :
marandi, g. urmia university - faculty of science - chemistry department, Urmia, Iran
Abstract :
An efficient procedure for the one-pot three-component synthesis of various 5-aryl- 1,3-dimethyl-6-alkylamino furo[2,3-d]pyrimidines using 1,3-dimethylbarbituric acid and isocyanides in the presence of aromatic aldehydes in water medium is reported. All products were obtained in good yields in simple reaction conditions.
Keywords :
Three component reactions , Furo[2 , 3 , d]pyrimidines , 1 , 3 , Dimethylbarbituric acid , Isocyanides , Aromatic aldehydes
Journal title :
Journal of Materials and Environmental Science
Journal title :
Journal of Materials and Environmental Science
