Title of article :
Assessment of antioxidant potential and α-amylase and acetylcholinesterase inhibitory activities of Urginea maritima (L.) Baker bulbs
Author/Authors :
maazoun, a. m. university of carthage - national institute of applied sciences and technology(insat), national agricultural research institute of tunisia(inrat) - laboratory of protein engineering and bioactive molecules(lip-mb), laboratory of biotechnology applied to agriculture (lbaa), tunisia , belhadj, f. university of carthage - national institute of applied sciences and technology( insat) - laboratory of protein engineering and bioactive molecules(lip-mb), Tunisia , ben jemâa, j. m. university of carthage - national agricultural research institute of tunisia(inrat) - laboratory of biotechnology applied to agriculture (lbaa), Tunisia , marzouki, m. n. university of carthage - national institute of applied sciences and technology(insat) - laboratory of protein engineering and bioactive molecules(lip-mb), Tunisia
Abstract :
Recently, there has been worldwide interest in finding new and safe antioxidants from natural sources because of their significance in treating various metabolic syndromes and chronic disorders. In this study, we aimed to evaluate the antioxidant potential of Urgineamaritima bulb extract. Numerous in vitro models were used in order to highlight the antioxidant potential of the methanolic extract of U. maritima bulbs. In addition, the effects of U. maritima bulbs extract against α-amylase and acetylcholinesterase activities were explored. Results indicated that U. maritima bulbs extract exhibited a high antioxidant potential in the various invitro systems. Moreover, the investigation of the protective effect of U. maritima bulb extract against induced lipid peroxidation in a biological matrix showed its effective protection. In addition, U. maritima bulb extract revealed an important inhibitory power against α-amylase (IC_50 = 95.03 ± 1.29 μg/mL) and acetylcholinesterase (IC_50 = 72.19 ± 1.48 μg/mL) activities.
Keywords :
Urginea maritima , Antioxidant activity , α , amylase activity inhibition , Acetylcholinesterase activity inhibition
Journal title :
Journal of Materials and Environmental Science
Journal title :
Journal of Materials and Environmental Science
