Title of article
Efficient Synthesis of 2-Aroyl-3-Alkoxy-2,3-Dihydrothiazolo[2,3-c][1,2,4]Triazol-5(6H)-ones
Author/Authors
Al-Talib, Mahmoud Yarmouk University - Chemistry Department, Jordan , Al-Saad, Dalia Yarmouk University - Chemistry Department, Jordan , Shkoor, Mohanad Yarmouk University - Chemistry Department, Jordan , Tashtoush, Hasan I. Yarmouk University - Chemistry Department, Jordan
From page
317
To page
323
Abstract
Aryl carboxylic acid N -(4-oxo-4,5-dihydro-thiazol-2-yl)hydrazides (4a-g) were prepared from the reactions of 2-carbethioxymethylthio-2-thiazoline-4-one (2) with alkyl or aryl hydrazides (3a-g), in ethanol at room temperature. The reactions of compounds 4a-g with methyl and ethyl orthoformates afforded 2-aroyl-3-alkoxy-2,3-dihydrothiazolo[2,3-c][1,2,4]triazol-5(6H)-ones (5a-n). All newly synthesized compounds were fully characterized using Mass spectrometry, IR, 1H-NMR, 13C-NMR spectroscopy, and elemental analysis.
Keywords
Thiazolotriazoles , Trimethyl orthoformate , Triethylorthoformate
Journal title
Jordan Journal of Chemistry
Journal title
Jordan Journal of Chemistry
Record number
2585081
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