Synthesis, Characterization and Biological Studies of Some Transition Metal Chelates Derived from Hydrazone Schiff Base Ligand

Complexes of Mn(II), Co(II), Ni(II), Cu(II), Ti(III), Cr(III), Fe(III), Zr(IV) and UO2(VI) with a Schiff base ligand derived from 2-hydroxy-5-methyl-3-nitroacetophenone and 2-hydroxybenzohydrazide have been prepared. The complexes have been characterized on the basis of elemental analysis, IR and electronic spectra, magnetic moment and thermogravimetric analysis. From the analytical data, the stoichiometry of the complexes has been found to be 1: 1 (metal: ligand).The physicochemical data suggest octahedral geometry for all the complexes except Cu(II). The Cu(II) complex shows square planar geometry. The thermal data of prepared compounds have been analyzed and various kinetic parameters have been evaluated according to the Horowitz-Metzger method. The solid- state electrical conductivity of synthesized compounds has been measured in pellet form and the complexes are found to have a semiconducting nature. The ligand and its complexes have also been tested for their antimicrobial behavior against E. coli, S. typhi, P. aeruginosa and S. aureus by the disc diffusion method. The Scanning electron micrograph (SEM) of the ligand and its Cu(II) complex have been studied. The Mn(II) complex has been studied by means of powder XRD and was found to be crystalline.