Author/Authors :
Mohamed, Abdul Azeem AI-Azhar University - Faculty of Medicine for Male - Obstetric and Gynecology, Egypt , El-Daghestani, Mohamed Um Al-Qura University - Obstetrics and Gynecology Department, Saudi Arabia , El-Shiekha, Khaled Z. AI-Azhar University - Faculty of Medicine for Male - Obstetric and Gynecology, Egypt , Gabreel, Mohamed AI-Azhar University - Faculty of Medicine for Male - Obstetric and Gynecology, Egypt , Soliman, Salah AI-Azhar University - Faculty of Medicine for Male - Obstetric and Gynecology, Egypt
Abstract :
Objectives: The purpose of this study was to compare the long-term efficacy of the levonorgestrel intrauterine system and transcervical resection of the endometrium in the treatment of perimenopausal idiopathic menorrhagia. Materials and Methods: This study was an open, randomized 2-years clinical trial. Patients with idiopathic menorrhagia were assigned randomly to either the levonorgestrel intrauterine system (n = 30) or endometrial resection (n = 30). Total bleeding score/month was used to evaluate the menstrual blood loss. Discontinuations and cases requiring repeat operations were evaluated. Results:Total bleeding score/month decreased from a baseline median of 49.9 to 11.4 (P .01) for the levonorgestrel intrauterine system and from 53.6 to 12.6 (P .0J) for transcervical resection of the endometrium. Twenty six women of thirty using the levonorgestrel intrauterine system completed the 2-year follow-up compared with twenty seven of twenty nine for transcervical resection of the endometrium. Conclusion: Both treatments levonorgestrel intrauterine system and transcervical resection of the endometrium efficiently reduced menstrual bleeding. The high continuation rate suggests that the levonorgestrel intrauterine system is comparable with transcervical resection of the endometrium.
