What’s New: Team-Based Learning Applied to a Medicinal Chemistry Course

Team-based learning (TBL) is a teaching technique that was developed in the late 1970s by Larry Michaelsen in the Business School of the University of Oklahoma, Norman, Okla., USA. Recently, TBL has been applied to courses in the pharmacy curricula. Here I describe my experience using TBL methodology in a medicinal chemistry course I recently taught. Medicinal chemistry encompasses a number of important concepts related to the chemical structure of drug molecules, including pKa and pH behavior, solubility, stability, absorption, distribution, metabolism, excretion, and structure-activity relationships.