• Title of article

    Personalizing Radiation Treatment Delivery in the Management of Breast Cancer

  • Author/Authors

    Ahmed, Kamran A. Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Daniel Grass, G Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Orman, Amber G. Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Liveringhouse, Casey University of South Florida College of Medicine - Tampa - FL 33612, USA , Montejo, Michael E. Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Soliman, Hatem H. Department of Breast Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Han, Heather S. Department of Breast Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Czerniecki, Brian J. Department of Breast Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Torres-Roca, Javier F. Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA , Diaz, Roberto Department of Radiation Oncology - H. Lee Moftt Cancer Center and Research Institute - Tampa - FL 33612, USA

  • Pages
    9
  • From page
    1
  • To page
    9
  • Abstract
    Long-term data establishes the efcacy of radiotherapy in the adjuvant management of breast cancer. New dose and fractionation schemas have evolved and are available, each with unique risks and rewards. Current eforts are ongoing to tailor radiotherapy to the unique biology of breast cancer. In this review, we discuss our eforts to personalize radiotherapy dosing using genomic data and the implications for future clinical trials. We also explore immune mechanisms that may contribute to a tumor’s unique radiation sensitivity or resistance.
  • Keywords
    Personalizing , Radiation Treatment Delivery , Breast Cancer
  • Journal title
    International Journal of Breast Cancer
  • Serial Year
    2018
  • Full Text URL
    downloads.hindawi.com/journals/ijbc/2018/6729802.pdf
  • Record number

    2585608

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2585608