Author/Authors :
Sahin, Omer Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Akpek, Mahmut Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Sarli, Bahadir Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Baktir, Ahmet Oguz Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Savas, Goktug Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Karadavut, Serhat Erciyes University - Kayseri Education and Research Hospital, School of Medicine - Department of Cardiology, Turkey , Elcik, Deniz Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Saglam, Hayrettin Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Kaya, Mehmet Gungor Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey , Arinc, Huseyin Erciyes University - School of Medicine, Kayseri Education and Research Hospital - Department of Cardiology, Turkey
Abstract :
Objectives: The aim of this study was to evaluate the association of the levels of red blood cell distribution width (RDW) with the severity of atherosclerosis and to determine whether or not the RDW level on admission is an independent predictor of all-cause mortality in patients with non-ST elevation myocardial infarction (NSTEMI). Materials and Methods: A total of 335 consecutive patients with NSTEMI were enrolled in this study. The patients were divided into high (n = 105) and low (n = 230) SYNTAX groups. The high SYNTAX group was defined as patients with a value in the third tertile (SYNTAX score, SXscore ≥ 12), while the low SYNTAX group was defined as those with a value in the lower 2 tertiles (SXscore 12). The high RDW group (n = 152) was defined as patients with RDW 14.25% and the low RDW group (n = 183) as those with RDW ≤ 14.25%. All-cause mortality was followed up to 38 months. Results: The mean follow- up period was 18 ± 11 months. The RDW levels of patients were significantly higher in the high SYNTAX group than in the low SYNTAX group (15.2 ± 1.8 vs. 14.2 ± 1.2, p 0.001). Pearson’s coefficients were used to determine the degree of association between RDW levels and SXscore and also between RDW levels and high-sensitivity C-reactive protein. There was a significant correlation between RDW levels and SXscore (r = 0.460, p 0.001). Also, there was a significant correlation between RDW levels and high-sensitivity Creactive protein (r = 0.180, p = 0.001). All-cause mortality rate was not significantly different between the high and low RDW groups (log-rank, p = 0.621). Conclusion: RDW levels were independently associated with high SXscore but were not associated with long-term mortality in NSTEMI patients.
