Author/Authors :
Hamza, Yasser University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , Nabawi, Ayman University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , Alwagieh, Hatem University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , Koraitim, Tarek University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , Khalil, Rafik University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , El-Hammadi, Habashi University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt , Aboul Soud, Abdel Kader University of Alexandria - Faculty of Medicine - Department of Surgery, Egypt
Abstract :
Aim: The aim of this work was to evaluate the concept of Sentinel Lymph Node Biopsy (SLNB) in the management of thyroid cancer as regards feasibility and its impact on the decision-making. Methods: The study included 45 patients with differentiated thyroid cancer. At operation the thyroid tumour was exposed, 1.0% isosulfan blue dye was injected into it. When the dye stained a lymph node, the latter was marked and labeled as the sentinel lymph node (SLN). Total thyroidectomy and bilateral central neck dissection was then completed. The tumour and the nodes were examined histologically. Results: SLNs were detected in 24 patients (60%). All of them showed single stained nodes. All SLNs were level VI. All were located on the same side of the tumour, inferior to the location of the inferior thyroid artery. Eighteen (75%) SLNs were invaded by malignant tissue. The remaining 6 SLNs (25%) were free of malignancy. This was confirmed by immunohistochemical staining. Conclusion: According to the findings of the study, Sentinel Lymph Node (SLN) detection is a feasible technique. When successful, it is also a reliable one
