Author/Authors :
heshmat, ramin tehran university of medical sciences - chronic diseases research center, endocrinology and metabolism population sciences institute, Tehran, Iran , hemati, zeinab isfahan university of medical sciences - child growth and development research center, research institute for primordial prevention of noncommunicable disease - pediatrics department, Isfahan, Iran , qorbani, mostafa alborz university of medical sciences - non-communicable diseases research center, Karaj, Iran , qorbani, mostafa tehran university of medical sciences - endocrinology and metabolism research center, endocrinology and metabolism clinical sciences institute, Tehran, Iran , nabizadeh asl, laleh tehran university of medical sciences - chronic diseases research center, endocrinology and metabolism population sciences institute, Tehran, Iran , nabizadeh asl, laleh hacettepe university - faculty of health sciences - department of nutrition and dietetics, Ankara, Turkey , motlagh, mohammad esmaeil ahvaz jundishapur university of medical sciences - pediatrics department, Ahvaz, Iran , ziaodini, hasan ministry of education and training - bureau of health and fitness, Tehran, Iran , taheri, majzoubeh ministry of health and medical education - office of adolescents and school health, Tehran, Iran , ahadi, zeinab tehran university of medical sciences - chronic diseases research center, endocrinology and metabolism population sciences institute, Tehran, Iran , shafiee, gita tehran university of medical sciences - chronic diseases research center, endocrinology and metabolism population sciences institute, Tehran, Iran , aminaei, tahereh ministry of health and medical education - office of adolescents and school health, Tehran, Iran , hatami, hooman alborz university of medical sciences - student research committee, Karaj, Iran , kelishadi, roya isfahan university of medical sciences - child growth and development research center, research institute for primordial prevention of noncommunicable disease - pediatrics department, Isfahan, Iran
Abstract :
Introduction: Metabolic syndrome (MetS) is one of the common metabolic disorders seen in children and adolescents. This study aims to assess the rate of the MetS and its associated factors in a nationally-representative sample of Iranian pediatric age groups. Methods: This nationwide cross- sectional study was designed in 2015 in 30 provinces of Iran. Participants consisted of 4,200 school students, aged 7-18 years, studied in a national school-based surveillance program (CASPIAN-V). Physical examination and laboratory tests were performed using standard protocols. Blood samples were drawn from 3834 students for biochemical tests. Results: The participation rate for blood sampling was 91.5%. MetS was significantly more prevalent among students in urban than in rural areas (5.7% vs. 4.8%, P value 0.01). MetS was more prevalent in students with obese parents than in those with non-obese parents (6.4% vs. 4.5%, P value 0.05). Significant association existed between moderate level of healthy nutritional behaviors and MetS after controlling for potential confounders (odds ratio [OR]: 0.62, 95% CI: 0.40-0.98). Students with high unhealthy nutritional behaviors showed an increased risk of MetS in crude (OR: 1.6, 95% CI: 1.05-2.44) and adjusted model (OR: 1.65, 95% CI: 1.05-2.63). Conclusion: High rate of MetS and associated risk factors was observed in Iranian pediatric age groups, with higher rates among boys. These findings provide useful information for effective preventive strategies based on diet, exercise, and lifestyle modification rather than therapeutic modalities.
