Author/Authors :
Karim, Shahid Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Jafri, Wasim Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Faryal, Afsheen Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Majid, Shahid Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Salih, Mohammad Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Jafri, Fatima Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Hamid, Saeed Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Shah, Hasnain Ali Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Nawaz, Zohaib Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan , Tariq, Usman Aga khan University Hospital - Department of Medicine, Out Patients Department, Section of Gastroenterology, Pakistan
Abstract :
Objectives: To evaluate the correlation of gastroesophageal reflux disease (GERD) symptoms with routine post dinner physical activity and time interval before going to bed, in multiethnic South Asian population.Methods: Prospective, cross sectional analytical, multicenter study was conducted from February 2009 to March 2010.Patient s relative sitting in outpatient clinics with no comorbids, nonsmoker and non alcoholic were included.They were asked to fill a validated GERD questionnaire and were also inquired about routine post dinner physical activity (lying, sitting, walking) and dinner-bed time interval. Odds Ratios (OR) and their 95% Confidence Intervals (CI) were estimated using Logistic Regression, with gastroesophageal reflux (GER) symptoms as an outcome.Results: Subjects analyzed were 1875. Mean age was 35.37 ± 12.69 years of which 689 (36.74%) had GERD symptoms. GERD symptoms were 42.08% in routine post dinner recumbency position. While 35.17% and 30.52% had the symptoms in post dinner sitting and walking before going to bed [OR for walking 0.66(95% CI 0.5-0.88) when compared with lying posture]. GERD symptoms were 45.86 % among those with dinner-bed time of one hour, progressively decreasing to 41.68 %, 31.45 % and 29.88 % in the second, third and forth hour respectively. Odds ratio was significant only at 3rd [0.55(0.41-0.74)] and ≥ 4th hr [0.51(0.37-0.71)] when compared with first hour.Conclusion: Regular post dinner walk and 3 hour dinner-bed time interval were less associated with GERD symptoms.
