Title of article
Unidimensional Thin Layer Chromatography of Salicylic Acid Derivatives on Boric Acid-Impregnated Plates in Drugs Studies
Author/Authors
Ahmad Panahi, H. islamic azad university - Department of Chemistry, ايران , Moniri, E. islamic azad university, ايران , Izadi, A. islamic azad university - Department of Chemistry, ايران , Parvin, M. M. islamic azad university - Department of Chemistry, ايران , Rahimi, A. islamic azad university - Department of Chemistry, ايران , Manoochehri, M. islamic azad university - Department of Chemistry, ايران
From page
53
To page
58
Abstract
A unidimensional Thin Layer Chromatography system for the separation of salicylic acid and its derivatives (sulfosalicylic acid and Aspirin) has been developed. The separation was successfully using a solvent system of chloroform-methanol-water-ammonium hydroxide 120:75:6:2 (VN) as mobile phase on TLC plates impregnated with boric acid. The method is based on different behavior of investigated compounds in impregnated TLC plates with different amount of boric acid. The effect of boric acid contents of TLC plates on separation factors like resolution (R,), capacity factor (k ) and selectivity factor (a) were investigated.
Keywords
Thin Layer Chromatography (TLC) , Aspirin , Salicylic Acid , Sulfosalicylic Acid
Journal title
Quarterly Journal of Applied Chemical Research (JACR)
Journal title
Quarterly Journal of Applied Chemical Research (JACR)
Record number
2591818
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