Title of article
Transient Myeloproliferative Disorder and Down Syndrome: Is there a link?
Author/Authors
Reyes, Zenaida S. Sultan Qaboos University Hospital - Department of Child Health, Oman , Bashir, Wafa Sultan Qaboos University Hospital - Department of Haematology, Oman , Pathare, Anil Sultan Qaboos University Hospital - Department of Haematology, Oman
From page
498
To page
502
Abstract
An extremely premature male neonate presented with an unusual multisystem dysfunction within the first 24 to 48 hours of life. The unfolding of clinical events and investigations revealed a transient myeloproliferative disorder (TMD). TMD was the main indication for karyotyping of this premature infant without clinical symptoms of Down syndrome. The awareness of TMD in a newborn warrants karyotype analysis to look for trisomy 21 and a close surveillance because of its potential progression to true leukaemia
Keywords
Extreme premature , Transient myeloproliferative disorder , Down syndrome , GATA1 , Acute myelogenous leukemia (AML) , Case report , Oman
Journal title
Sultan Qaboos University Medical Journal (SQUMJ)
Journal title
Sultan Qaboos University Medical Journal (SQUMJ)
Record number
2592390
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