‎In vitro‎ assessment of anti-Trichomonas effects of Zingiber officinale‏ ‏and ‎Lavandula angustifolia alcoholic extracts on Trichomonas gallinae

Trichomonas gallinae is a parasite that acts as a cankercausing agent and leads to significant loss and mortality, especially in young birds. Metronidazole is the approved drug used for the treatment of trichomoniasis. A nonchemical alternativess such as medical plant extracts are also used to treat this disease due to drug resistance. This study aimed to assess in vitro antitrichomonal effects of Lavandula angustifolia and Zingiber officinale extracts on T. gallinae compared with metronidazole. The T. gallinae samples were obtained from infected pigeons. Multiwell plates filled with different concentrations (5.00, 10.00, 25.00, 50.00, and 100 μg mL1) were used to perform in vitro analysis. The Z. officinaleextract’s minimum inhibitory concentration (MIC) in the 24hr period was 25.00 μg mL1, while it was 50.00 μg mL1 for metronidazole. The MIC value obtained for L. angustifolia extract in 24hr was 50.00 μg mL1. The results indicated that the extracts of Z. officinaleand L. angustifolia could act as potential natural agents against trichomoniasis. Furthermore, this study delineated the equal efficiency of L. angustifolia and Z. officinale with that of metronidazole in inhibiting the growth of Trichomonas gallinae trophozoites in culture media.