• Title of article

    Pathomorphological Studies on the Effect of Aged Garlic Extract in Aflatoxin B1 Induced Liver Damage in Wistar Albino Rats

  • Author/Authors

    Krishnappa, Sarvesha Department of Pathology - Veterinary College - Hebbal - KVAFSU, Bengaluru , Satyanarayana, Mayasandra Lakshmikanth Department of Pathology - Veterinary College - Hebbal - KVAFSU, Bengaluru , Rao, Suguna Department of Pathology - Veterinary College - Hebbal - KVAFSU, Bengaluru , Yathiraj, Sreenivasa Veterinary College - Hebbal - KVAFSU, Bengaluru , Shridhar, Narayana Bhat Department of Pharmacology and Toxicology - Veterinary College - Hebbal - KVAFSU, Bengaluru , Yamanappa Mukartal, Shivalingappa Department of Veterinary Microbiology - Veterinary College - Hebbal - KVAFSU, Bengaluru , Gupta, Saurabh Division of Animal Health - Central Institute for Research on Goats (CIRG) - Makhdoom - PO-Farah - Uttar Pradesh, India , Singh, Shoorvir Division of Animal Health - Central Institute for Research on Goats (CIRG) - Makhdoom - PO-Farah - Uttar Pradesh, India , Dhama, Kuldeep Division of Pathology - Indian Veterinary Research Institute (IVRI) - Bareilly, Uttar Pradesh , Elattuvalappil, Anuradha Menon ICAR NAE Project - Veterinary College - Bengaluru, India

  • Pages
    7
  • From page
    648
  • To page
    654
  • Abstract
    The aim of the study was to evaluate the hepatoprotective effect of AGE in AFB1 induced liver damage in Wistar albino rats. Liver damage was induced by inoculating AFB1 (4 mg/kg BW) on day 12 of the experiment. AGE was used (200 mg/kg BW) orally, for a period of 28 days against AFB1 induced liver injury. Histopathologically there was periportal and centrilobular necrosis of hepatocytes and bile duct hyperplasia in AFB1 treated rats, however, when AGE was given along with AFB1 the hepatic parenchyma was apparently normal indicating the beneficial effect of AGE in protecting liver against AFB1 induced injury.
  • Keywords
    Aged garlic extract (AGE) , Aflatoxin B1 (AFB1) , Bile duct hyperplasia , Histhopathology
  • Journal title
    Advances in Animal and Veterinary Sciences
  • Serial Year
    2016
  • Full Text URL
    nexusacademicpublishers.com/uploads/files/AAVS_4_12_648-654.pdf
  • Record number

    2593965

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2593965