Blood Chemistry (Hematology) of Transfusion DependentBeta Thalassemia Patients at Hyderabad andAdjoining Areas

Present study was carried out to analyze quantitatively the blood parameters of TransfusionDependent Thalassemia (TDT) patients. A total number of seventy one (n=71) TDT patients aged04 to 26 yearswere selected from Fatimid foundationcenter, Hyderabad from June 2015 to May2016 and eighty four (n=84) control subjects (age, gender and locality matched persons withnegative personal and family history of thalassemia) were included inthis study. Blood sample of5mLwas collected from each participant to analyze white blood cells (WBC); total leukocytescounts (TLC); red blood cells (RBC); mean corpuscular value (MCV); mean corpuscularhemoglobin (MCH); mean corpuscular hemoglobin concentration (MCHC); hemoglobin (HB) andhematocrit (HCT). All the patients and control subjects were interviewed through a standardquestionnaire specially developed to study their life style and dietary habits. The collected datafrom TDT patients and control subjects was statistically analyzed by using p<0.05as statisticallysignificant variation between two groups. Results revealed significantly decreased levels of HCT,MCV, MCH and platelets in TDT patients as compared to control subjects. All TDT patients werefrequently undergoing blood transfusion withinthe age groups.