Comparative Study on Cassia fistula Versus Sodium Bicarbonate and Magnesium Hydroxide Against Lactic Acidosis in Goats

Current study was carried out to compare efficacy of cassia fistula versus sodium bicarbonate+magnesium hydroxide against lactic acidosis in goats. Thirty six goats of same age and sex were selected and divided into three groups viz. A, B and C. Goats in group A and B were induced lactic acidosis, while group was C kept as control. After the appearance of clinical signs, group A was treated with Cassia fistula and group B with sodium bicarbonate+magnesium hydroxide. All the goats were examined for the changes in physiological parameters at the interval of 24, 48 and 72 hours after treatments. Results indicated that clinical signs in induced lactic acidosis goats were decreased body temperature, ruminal and intestinal movement, ruminal pH and blood pH, while increased respiration and heart rate. Glucose level was 190.14±36.49 mg/dL, total bilirubin 0.75±0.04 mg/dL, direct bilirubin 0.27±0.03 mg/dL, indirect bilirubin 0.40±0.03 mg/dL, alanine aminotransferase 36.42±3.04 U/L and alkaline phosphatase 420±3.65 U/L. After the treatment group A showed increased rumen and intestinal motility, however the treatment with sodium bicarbonate+magnesium hydroxide (group B) helped in improving the normal physiological parameters but did not improve the rumen and intestinal motility. Serum biochemical changes were returned to the normal in both groups (A and B) within 72hrs, while the treatment with Cassia fistula resulted earlier recovery from the diseases. In conclusion, Cassia fistula administration in lactic acidosis is very effective for increasing the ruminal and intestinal motility and rapidly restoring all physiological parameters to normal range.