Title of article :
Association between ambient fine particulate matter with blood pressure levels among Iranian individuals admitted for cardiac and respiratory diseases: Data from CAPACITY study
Author/Authors :
Khosravi ، Alireza Hypertension Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Rajabi ، Hamid Reza Cardiac Rehabilitation Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Vakhshoori ، Mehrbod Heart Failure Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Rabiei ، Katayoun Pediatric Cardiovascular Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Hosseini ، Mohsen Department of Biostatics and Epidemiology - School of Public Health - Isfahan University of Medical Sciences , Mansouri ، Asieh Applied Physiology Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Roghani-Dehkordi ، Farshad Interventional Cardiology Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Najafian ، Jamshid Hypertension Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Rahimi ، Mojtaba Department of Anesthesiology - School of Medicine - Isfahan University of Medical Sciences , Jafari-Koshki ، Tohid Department of Statistics and Epidemiology - Molecular Medicine Research Center, School of Health - Tabriz University of Medical Sciences , Sadeghian ، Babak Central Laboratory and Air Pollution Monitoring, Isfahan Department of Environment - Isfahan Province Environmental Monitoring Center , Shishehforoush ، Mansour Isfahan Disaster Management Office - Isfahan Governor Office , Lahijanzadeh ، Ahmadreza Khouzestan Department of Environment , Taheri ، Marzieh Hypertension Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences , Sarrafzadegan ، Nizal Isfahan Cardiovascular Research Center, Cardiovascular Research Institute - Isfahan University of Medical Sciences
Abstract :
BACKGROUND: The relation between air pollution and cardiovascular diseases (CVDs) risk factors, especially blood pressure (BP) levels, has been less frequently assessed. The aim of this study was evaluating the association between air pollutants of less than 2.5 µm [particulate matter (PM2.5)] and BP indices among individuals admitted with CVDs and pulmonary diseases. METHODS: This cross-sectional study was in context of air pollution associated with hospitalization and mortality of CVDs and respiratory diseases (CAPACITY) study. Data of 792 Iranian patients referring to two hospitals in Isfahan, Iran, for cardiovascular or respiratory problems from March 2011 to March 2012 were used for analysis. BP indices including systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were obtained from patients’ medical forms and mean PM2.5 concentrations during 24 hours prior to admission of each patient were obtained from Isfahan Department of Environment (DOE). RESULTS: Mean ± standard deviation (SD) of participants’ age were 62.5 ± 15.9 years. All BP indices on admission were significantly higher in women compared with men. Adjustment of all potential confounders including age, sex, temperature, wind speed, and dew point revealed that increasing one quartile in PM2.5 concentrations had been associated with 1.98 mmHg raising in SBP at the time of admission [95% confidence interval (CI) = 0.41-3.54, P = 0.010]. Women with cardiac diseases had higher all BP indices with increased PM2.5 concentration [SBP: β: 4.30, 95% CI = 0.90-7.70, P = 0.010; DBP: β: 1.89, 95% CI = 0.09-3.69, P = 0.040; MAP: β: 3.09, 95% CI = 0.68-5.51, P= 0.010, respectively). CONCLUSION: Our findings suggest that increasing PM2.5 concentration has been positively associated with raising SBP in total population and all BP indices among women with cardiac problems at admission time. Several comprehensive studies are required for confirming these relations.
Keywords :
Particulate Matter , Blood Pressure , Air Pollutants , Air Pollution
Journal title :
Arya Atherosclerosis
Journal title :
Arya Atherosclerosis
