Factors Affecting Prognosis in Upper Urinary System Urothelial Tumors: 15 Years Clinical Experience

Purpose: It is aimed to determine retrospectively evaluate oncological results of cases withupper urinary system urothelial tumors in our clinic for the last 15 years. Material and Methods: Records of 32 cases in our clinic January 1992-December 2006 were evaluated retrospectively. Evaluated parameters are age, complaint; tumor localization, grade and stage, applied treatment choice, follow-up period, lifetime without illness, time until tumor recurrence. Results: Median age was 60 (30-82 years), mean follow-up period was 23 months (3-118 months). In follow-up period, tumor recurred in fourteen cases. Tumor was defined as low and high grades in twenty two (69%) (%68,75) and ten (31%) (%31,25) cases, respectively; and tumor was determined in fourteen (44%) (%43,75), five(16%) (%15,63), six(18%) (%18,75), five(16%) (%15,63) and two cases (6%) (%6,26), in Ta, T1, T2, T3, T4 stages, respectively. Seven patients (22%) (%21,88) are still alive and mean follow-up period is 39 months (11-118 months). Nineteen patients (60%) (%59,38) whose mean follow-up period was 24 months (0.5-56 months) died because of the illness. When their durations of survival are considered, it was found there was a statistically significant difference between tumor stage and survival duration and that, however, there was no meaningful difference between tumor grade and survival duration. Conclusion: Tumor stage was defined as the most important prognostic factor for upper urinary system urothelial tumors.