Possible Healing Effects of Aloe Barbadensis on Nephrotoxicity Induced by Soybean Oil in Rats

Purpose: This study aimed to analyze the effects of Aloe barbadensis on kidney. Material and Methods: Eighteen Wistar Albino female rats were used for the experiment. They were divided into 3 groups. Biopsy materials were taken from the right kidneys of the rats and were analyzed under the light microscope. Results: Biopsy materials, which were taken from the kidneys of the control subjects, revealed normal structural features of renal cortex and medulla. No distinctive differencewas found in the Malpighi corpuscles in the group receiving Aloe Barbadensis. However, various degrees of vacuolization in the proximal tubules, and the complete loss of structural characteristics of proximal tubules were observed. Vacuolization was rarely seen in distal tubules. Congestion was clear in the medulla. In the third group receiving only soybean oil, a distinctive congestion was observed in all glomerulus and in the medulla. The detected pathologic changes were more common and severe in the third experiment group that received only soybean oil. Congestion in glomerulus was mostly observed in this group. Conclusion: These results lead us to consider that Aloe barbadensis plays a healing role against the toxic effects of soybean oil on the kidney.