Comparison of Effect of Intraarticularly Delivered Levobupivacaine Morphine and Tramadol Combinations on Postoperative Analgesia Following Arthroscopic Knee Surgery

Objective: We compared the effects of intraarticularly administered levobupivacaine, morphine and tramadol combinations used for postoperative analgesia after arthroscopic knee surgery. Material and Methods: Sixty six patients who underwent arthroscopic knee surgery were divided randomly into three groups as follows. Patients in group L received 100 mg levobupivacaine, group LM received 100 mg levobupivacaine+10 mg morphine, and group LT received 100 mg levobupivacaine + tramadol via intraarticular route 10 minutes before tourniquet deflation. Visual analog scores were recorded at 5th, 10th, 30th, and 60th minutes, 2nd, 6th, 12th, and 24th hours, and on 3rd and 7th postoperative days. Additional analgesic was administered to patients whom VAS was ≥5. Results: No difference was found regarding demographic and hemodynamic data. Postoperative analgesia was found to be effective in all of the groups. There was no difference when comparing postoperative hemodynamic parameters and sedation levels between the groups. The groups were also statistically similar regarding additional analgesia requirements. Conclusion: We concluded that administration of levobupivacaine alone, levobupivacaine plus morphine, and levobupivacaine plus tramadol intraarticularly during arthroscopic knee surgery provided effective postoperative analgesia.