LETTER TO THE EDITOR: Complex Regional Pain Syndrome and Spontaneous Pain Following Simple Incision With Immobilization: A Case Report

Complex regional pain syndrome (CRPS) is characterized by vasomotor and sudomotor changes. Its etiology generally includes trauma, fracture, stroke, and coronary disease. It is evaluated in two subtypes: CRPS type I (reflex sympathetic dystrophy), presenting with complex regional pain syndromes accompanied by spontaneous pain, hyperalgesia, allodynia, edema, autonomic anomalies, and trophic changes; regional pain occurring after minor injuries and fractures in the extremities; and coexisting vasomotor, sudomotor changes, and sensorial changes, and CRPS type II (coxalgia), including major peripheral nerve injuries, in addition to all of these symptoms (1, 2). Although the pathogenesis of CRPS is not exactly known, peripheral and central sensitization, which causes neurogenic inflammation, is held responsible.