Hallermann–Streiff Syndrome—Confluence of Systems!

The purpose was to report a case of Hallermann–Streiff syndrome (HSS) with atypical presentation and present a brief literature review. Hallermann in 1948 and Streiff in 1950 described patients characterized by “bird face,” congenital cataract,mandibular hypoplasia, and dental abnormalities. The new syndrome was later defined as HSS, underlining the differences with regard to Franceschetti’s mandibulofacial dysostosis. HSS is associated with developmental anomalies involving structures of ectodermal origin (the face, scull, hair, skin, eyes, and teeth) and overall growth and development. Approximately 150 cases have been reported in the literature worldwide.