Title of article
ROLE OF HYDROGEN SULFIDE (H2S) IN CELL SIGNALING AND ATHEROSCLEROSIS: A REVIEW
Author/Authors
othman, mohd izani universiti teknologi mara cawangan pulau pinang, kampus bertam - faculty of pharmacy, MALAYSIA
From page
30
To page
37
Abstract
Hydrogen sulfide (H_2S) has been known for decades as a toxic gas. However, this gas has been discovered to be synthesised enzymatically in human tissues and is regarded as a novel gasotransmitter. H_2S is a signaling molecule that involves and governs many biological functions of the body. It has been shown that H_2S is associated with various disease conditions such as acute pancreatitis, sepsis, inflammation and atherosclerosis development. Current therapeutic approach may not benefit all patients with atherosclerosis. Therefore, the role of H2S as an anti-atherosclerotic agent has been the spotlight of cardiovascular medicine. Moreover, its implications in other diseases have also been studied extensively in order to develop new therapeutic approaches.
Keywords
hydrogen sulfide (H_2S) , atherosclerosis , reactive oxygen species (ROS) , signaling molecule , oxidative stress , oxidised low density lipoprotein (oxLDL)
Journal title
Esteem Academic Journal
Journal title
Esteem Academic Journal
Record number
2597964
Link To Document