Title of article
Drug Induced Gingival Overgrowth and Its Management
Author/Authors
Kazancıoğlu, H. Oğuz Bezmialem Vakıf Üniversitesi - Diş Hekimliği Fakültesi - Ağız Diş Çene Hastalıkları ve Cerrahisi A D, Turkey , Erişen, Merve İstanbul Üniversitesi - Diş Hekimliği Fakültesi - Ağız, Diş ve Çene Cerrahisi A D, Turkey , Demirtaş, Nihat Bezmialem Vakıf Üniversitesi - Diş Hekimliği Fakültesi - Ağız Diş Çene Hastalıkları ve Cerrahisi A D, Turkey , Türkmen, Aydın İstanbul Üniversitesi - İstanbul Tıp Fakültesi - Dahiliye A D Nefroloji B D, Turkey , Ak, Gülsüm İstanbul Üniversitesi - Dişhekimliği Fakültesi - Ağız, Diş, Çene Hastalıkları ve Cerrahisi Ana Bilim Dalı, Turkey
From page
66
To page
72
Abstract
Gingival overgrowth (GO) that associated with phenytoin tharapy was first reported in the dental literature in 1939 by Kimball. Recently, cyclosporine and numerous calcium channel blocker agents have been associated with GO. The etiology of drug-induced GO is not entirely understood but is clearly multifactorial. Some of the risk factors known to contribute to GO include the presence of gingival inflammation, presence of dental plaque, the depth of the periodontal pocket on probing, and the dose and duration of cyclosporine therapy. An oral medicine specialist and a periodontist should monitor patients with GO for as long as they receive therapy with cyclosporine, phenytoin, or calcium channel blockers to evaluate and treat oral complications from medical therapy.
Keywords
Gingival overgroth , cyclosporine , phenytoin , calcium channel blockers
Journal title
European Oral Research
Journal title
European Oral Research
Record number
2598552
Link To Document