Author/Authors :
Saleem, Uzma Department of Pharmacology - Faculty of Pharmaceutical Sciences - G.C. University - Faisalabad, Pakistan , Ejaz-ul-Haq, Muhammad Department of Pharmacology - Faculty of Pharmaceutical Sciences - G.C. University - Faisalabad, Pakistan , Chudary, Zunera Department of Pharmacology - Faculty of Pharmaceutical Sciences - G.C. University - Faisalabad, Pakistan , Ahmad, Bashir Riphah Institute of Pharmaceutical Sciences - Riphah International University - Lahore campus, Pakistan
Abstract :
Annona muricata L. (Annonaceaefamily) is a tropical plant and most prominently known for its edible fruit which has more medicinal properties but some effects are toxic. This review most commonly represents the phytochemical contents, pharmacological and biological actions and at someextent toxicological effects which depends on dose, solvent for extraction and part of plant used.More than 200 compounds have been isolated and identify from different parts of this plant. Phenols, alkaloids and acetogenins are the most important and effective compounds. Traditionally, Annona muricatais being used to treat diverse ailments such as inflammation, fever, pain, hypertension, diabetes, liver damage, bacterial infection and cancer. Pharmacologically, plant possessed antioxidant, anti-inflammatory, anti-diabetic, anti-hypertensive, anti-nociceptive, anxiolytic, anti-pyretic, wound healing, hepatoprotective, antibacterial, antiviral phyto-chemicals and extracts of this plant have been characterized as hypoglycemic, hepatoprotective, and wound healing activities and cytotoxic, insecticidal, anti-bacterial, anti-viral activities. It could be concluded that the use of Annona muricata fruit would be beneficial for having good health.
