Title of article
Effects of Sodium Selenite Supplementation on Lead Nitrate-induced Oxidative Stress in Lung Tissue of Diabetic and Non-diabetic Rats
Author/Authors
APAYDIN, Fatma Gökçe Gazi Üniversitesi - Faculty of Science - Department of Biology, Turkey , KALENDER, Suna Gazi Üniversitesi - Gazi Education Faculty - Department of Science Education, Turkey , DEMIR, Filiz Gaziosmanpasa University - Faculty of Arts and Sciences - Department of Biology, Turkey , BAS, Hatice Bozok University - Faculty of Arts and Science - Department of Biology, Turkey
From page
847
To page
853
Abstract
In this study, diabetic and non-diabetic male rats were given to sodium selenite, lead nitrate and sodium selenite plus lead nitrate through gavage. At the end of the 4th week, lipid peroxidation and antioxidant enzyme activities were investigated compared to control group. No significant differences were observed between control and sodium selenite treated groups. By the end of the fourth week, lead nitrate led to increase the levels of MDA, and decrease in antioxidant enzyme activities compared with the control group in diabetic and nondiabetic rats. As a result, sodium selenite significantly reduces lead nitrate induced lung toxicity in diabetic and non-diabetic groups.
Keywords
Lead nitrate , sodium selenite , oxidative stress , diabetes , lung
Journal title
Gazi University Journal Of Science
Journal title
Gazi University Journal Of Science
Record number
2600741
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