Title of article :
WEB-BASED REPOSITORY FOR SPATIAL MONITORING VIRAL TICK-BORNE PATHOGENS
Author/Authors :
Molorodov, Yu.I. Institute of Computational Technologies SB RAS, Novosibirsk, Russia , Chernenko, V.V. Novosibirsk University, Novosibirsk, Russia , Fedotov, A.M. Institute of Computational Technologies SB RAS, Novosibirsk, Russia
Abstract :
A study of the genetic diversity of tick-borne encephalitis (TBE) in the samples of
individual ticks I. persulcatus and I. pavlovskiy, is one of the urgent problems of modern molec-
ular biology and bioinformatics to come after 2000, “the post-genomic era”. Basically, this is
due to the complete sequencing of genomes as part of large-scale international programs. This
study suggests combining existing computer resources and databases on molecular biology.
An important task of research in this direction was to evaluate the molecular and genetic
diversity of bacteria Borrelia spp. Circulating on the territory of Siberia. For further culti-
vation of the full genome sequencing was carried out two types of Borrelia, selected genetic
variants often detected in Western Siberia. Another of the objectives is to determine the
molecular genetic diversity of potentially pathogenic microorganisms to humans (tick-borne
encephalitis virus, anaplasma, ehrlichia, babesia).
On the basis of factual material for the collection of mites in field expeditions on the
territory of the Altai, Kazakhstan and Siberia, and the results of whole genome sequencing,
developed the architecture and created a pilot version of an interactive information system
(IS), intended for the organization of the collection, storage and processing of field work,
resettlement and Migration ticks and they carry pathogens. With it built an interactive map
displaying locations of field gathering and habitat areas, including sections of publications
show the number of ticks and mites population by sex. The possibility of watching the
occurrence of infections and genes. Created block analysis of existing da
Keywords :
Interactivity , information systems , data integration , mites , sequencing , Lyme disease , encephalitis
Journal title :
Eurasian Journal of Mathematical and Computer Applications