Abstract :
Asthma is a disease characterized by hyper reactivity of the trachea and bronchi to reversible cither spontaneously or as a result of treatment. In this study serum magnesium, Zinc, and reduced glutathione levels were measured in order to determine their levels in the asthmatic patients and comparing these levels with healthy controls. Fifty- lour asthmatic patients were enrolled in the study and had their pulmonary function test, and the levels of Mg.Zn, and GSH. Serum magnesium and scrum zinc were determined by using Atomic Absorption Spectrophotometer . While serum glutathione was determined by spectrophotometry analysis. 1 he asthmatic patients were divided into four groups according to the interpretation of the pulmonary function test : severe expiratory flow limitation, moderate expiratory flow limitation , slight expiratory How limitation and normal lung values . In this study, it was found that serum magnesium levels in severe cases of asthmatic patients were significantly lower than the healthy control population [0.92 ± 0.17mmol / L vs. 1.01 ±0.19 mtnol /L; (p 0.05 )] while the other cases did not show any significant differences compared with the healthy control . As for scrum zinc levels, it was found that the slight cases of asthmatic patients were significantly higher than the healthy control [ 19.48 ± 1.93 // mol/L vs. 17.01 ± 2.94 // moI/L; (P 0.05 )]. However, the other cases did not show any significant differences compared with healthy control. While scrum glutathione levels in severe and slight cases of astlimatic patients were lower than the healthy control. [2.08 ± 0.51