Title of article :
A Study of Some Cellulose Derivatives As Hydrogel For Control Drug Release
Author/Authors :
E1-Azmirly, M.A. University of Baghdad - College of Education - Ibn Al-Haitham - Department of Chemistry, Iraq , Mukhlis, A.A University of Baghdad - College of Education - Ibn-Al-Haitham - Department of Chemistry, Iraq , Khallil, B.I. University of Baghdad - College of Education - Ibn-Al-Haitham - Department of Chemistry, Iraq
Abstract :
Neutral and semi-synthetic hydrophilic polymers are widely used in pharmaceutical technology to formulate as controlled release drugs delivery systems ,cellulose derivatives is biocompatibility, biodegradability , non-toxicity, its is a good candidate as drug carrier In this study, polymers were used as cellulosc derivatives like Methylcellulose (MC) Sodium Carboxymethylcellulose (NaCMC) as hydrogels for controlled delivery for Iwo kinds of drugs, Ccfotaxine Amoxycilline trihydrate in different media (Distilled water, Normal Saline Buffer solution PH=2). It has been shown that for sodium Carboxymethylcellulose the drug release rate is more than the Methylcellulose and that the release rate for Amoxycilline trihydrate is more than Cefotaxine.
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science