Title of article :
Synthesis of New Derivatives of P Lactam Antibiotics
Author/Authors :
Saud, M. D. University of Baghdad - College of Pharmacy, Iraq , AL- Mejwel, N. F. University of Baghdad - College of Pharmacy, Iraq , Sharrad, A. K. University of Basra - College of Pharmacy, Iraq
Abstract :
New Derivatives for Known (3- lactam antibiotics were synthesized utilizing the free amino group present in the parent compounds as the site for derivatization. The objectives for this study are to have new compounds which could have an increased potential resistance to the degradative enzymes knowing to be able to destroy the antibacterial activity of p- lactam antibiotics - Besides, these newderivatives could be congeners of known agents, or may be a potential pro-drugs for these agents.
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science