Serum And Bone Marrow Prostatic Speciafic Antigen And Prostatic Acid Phosphatase Levels In Patient s With Prostatic Cancer

Serum and bone marrow levels of prostatic specific antigen and prostatic acid phosphatase were analyzed and quantified by double antibody radioimmunoassay in 36 prostatic cancer patients, including 23 with metastatic cancer. There was a significant correlation between the serum and bone marrow levels of prostatic specific antigen and prostatic acid phosphatase independently of the metastases (p 0.001). No patient with prostatic cancer and positive bone marrow prostatic specific antigen or prostatic acid phosphatase levels had normal serum levels. Quantification of bone marrow prostatic specific antigen and prostatic acid phosphatase does not provide more information than does serum determination.