Title of article :
In vivo study of compounds 3-(acetyl Salicyloyl)-5,6 –Oisopropylidene- L-ascorbic acid ,2,3- (acetyl Salicyloyl)-5,6 –O-isopropylidene-L-ascorbic acid and 2,3,5,6- Tetra(acetyl Salicyloyl)-L-ascorbic acid
Author/Authors :
Maher, F. T. University of Baghdad - College of Education, Ibn Al-haithem - Department of Chemistry, Iraq , Mukhlis, A-J. Ministry of Science and Technology, Iraq , Abuod, A. I. Tikrit University - College of Science - Department of Chemistry, Iraq , Naji, N. A. University ofBaghdad - College of Education, Ibn Al-haithem - Department of Chemistry, Iraq
Abstract :
In vivo study was made for the coumpounds 3-(ocetyl Salicyloyl)-5,6-O-isoprpy lidene- L-ascorbicocid,2,3-(acetyl Salicyloyl )-5,6-o- isopropylidene-L-ascorbic acid and 2,3,5,6- (acetyl Salicyloyl )-L- ascorbic acid .And a measurement was mod for the concentration of the liberated aspirin in blood samples a fter (2,3,4,6,8,10) hours of the initial dose for the animal .The results showed that the highest concentration of aspirin was after four hours of giving the dose to the animal which is in accordance with pharmacokinetics studies
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science
Journal title :
Ibn Alhaitham Journal For Pure and Applied Science
