Author/Authors :
Saturveithan, C Department of Orthopaedics - Malacca General Hospital, Malaysia , Premganesh, G Department of Orthopaedics - Malacca General Hospital, Malaysia , Fakhrizzaki, S Department of Orthopaedics - Malacca General Hospital, Malaysia , Mahathir, M Department of Orthopaedics - Malacca General Hospital, Malaysia , Karuna, K Department of Orthopaedics - Malacca General Hospital, Malaysia , Rauf, K Department of Orthopaedics - Malacca General Hospital, Malaysia , William, H Department of Orthopaedics - Malacca General Hospital, Malaysia , Akmal, H Department of Orthopaedics - Malacca General Hospital, Malaysia , Sivapathasundaram, N Department of Orthopaedics - Malacca General Hospital, Malaysia , Jaspreet, K Department of Radiology - Malacca General Hospital, Malaysia
Abstract :
Introduction: Intra-articular hyaluronic acid (HA) is widely utilized in the treatment of knee osteoarthritis whereas platelet rich plasma (PRP) enhances the regeneration of articular cartilage. This study analyses the efficacy of HA and PRP in grade III and IV knee osteoarthritis.
Methodology: This is a cross sectional study with
retrospective review of 64 patients (101 knees) which
includes 56 knees injected with HA+ PRP, and 45 knees with
HA only.
Results: During the post six months International Knee
Documentation Committee (IKDC) evaluation, HA+PRP
group showed marked improvement of 24.33 compared to
12.15 in HA group. Decrement in visual analogue score
(VAS) in HA+PRP was 1.9 compared to 0.8 in HA group.
Conclusion: We propose intra-articular HA and PRP
injections as an optional treatment modality in Grade III and
IV knee osteoarthritis in terms of functional outcome and
pain control for up to six months when arthroplasty is not an option.
