Thromboembolism in Malignant Musculoskeletal Tumour:A Literature Review

Malignant musculoskeletal tumour may cause considerable burden to general health. (e fast growth combined with the tumourcharacteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignantmusculoskeletal tumourmaycausesignificantdisabilityby destroyingnormaltissuethatplaysimportantroleinbodykinematics.(romboembolism, including deep vein thrombosis, pulmonary embolism, and other kinds of venous thromboembolism, is oneof the most underestimated complications of musculoskeletal tumour. Normally, thrombosis ensues when pathologic factorsovercame the body hemostatic regulatory capabilities, which will predispose the body to the formation of thrombus. Venousthromboembolism in musculoskeletal tumour may develop as a result of interaction between the tumour pathologic capabilitiesand its interaction with normal bodily functions. In this study, we reviewed the burden of musculoskeletal tumour and itscomplicationonglobalhealth.(en,thereviewwillfocusonthepathologicandclinicalaspectofthromboembolisminmalignantmusculoskeletal tumour, including pathophysiology, diagnosis, and treatment based on recent findings and literature.