Author/Authors :
Feng, Zhihong Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China , Wang, Tao Department of Emergency Medicine - Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China , Liu, Ping Department of Physiology and Pathophysiology - Capital Medical University, Beijing, China , Chen, Sipeng Department of Public Health - Capital Medical University, Beijing, China , Xiao, Han Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China , Xia, Ning Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China , Luo, Zhiming Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China , Wei, Bing Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China , Nie, Xiuhong Department of Respiratory Medicine - Xuanwu Hospital - Capital Medical University, Beijing, China
Abstract :
We aimed to investigate the efficacy of four severity-of-disease scoring systems in predicting the 28-day survival rate among patients
with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) requiring emergency care. Clinical data of patients
with AECOPD who required emergency care were recorded over 2 years. APACHE II, SAPS II, SOFA, and MEDS scores were
calculated from severity-of-disease indicators recorded at admission and compared between patients who died within 28 days of
admission (death group; 46 patients) and those who did not (survival group; 336 patients). Compared to the survival group, the
death group had a significantly higher GCS score, frequency of comorbidities including hypertension and heart failure, and age
(𝑃 < 0.05 for all).With all four systems, scores of age, gender, renal inadequacy, hypertension, coronary heart disease, heart failure,
arrhythmia, anemia, fracture leading to bedridden status, tumor, and the GCS were significantly higher in the death group than the
survival group.Theprediction efficacy of the APACHEII and SAPS II scores was 88.4%.Thesurvival rates did not differ significantly
between APACHE II and SAPS II (𝑃 = 1.519). Our results may guide triage for early identification of critically ill patients with
AECOPD in the emergency department.
