Author/Authors :
Ibrahim, Wanis H. Department of Medicine - Hamad General Hospital and Weill-Cornell Medical College, Doha, Qatar , Rasul, Fatima Department of Medicine - Hamad General Hospital, Doha, Qatar , Ahmad, Mushtaq Department of Medicine - Hamad General Hospital, Doha, Qatar , Bajwa, Abeer S. Department of Medicine - Hamad General Hospital, Doha, Qatar , Alamlih, Laith I. Department of Medicine - Hamad General Hospital, Doha, Qatar , El Arabi, Anam M. Department of Medicine - Hamad General Hospital, Doha, Qatar , Al-Mohannadi, Dhabia Department of Medicine - Hamad General Hospital, Doha, Qatar , Siddiqui, Mohammed Y. Department of Medicine - Hamad General Hospital, Doha, Qatar , Al-Sheikh, Israa S. Hamad General Hospital, Doha, Qatar , Ibrahim, Azdin A. St. Josefs Hospital, Wiesbaden, Germany
Abstract :
Data on inhaler technique and its effects on maternal and fetal outcomes during pregnancy are seldom reported. +e primary
objective of this study was to evaluate inhaler technique and identify errors in inhaler use among pregnant women with asthma.
Secondary objectives were to identify factors associated with poor inhaler technique and study the association between inhaler
technique and maternal and fetal outcomes. +is was a cross-sectional, face-to-face, prospective study of 80 pregnant women with
physician-diagnosed asthma. Seventy-three and 41 asthmatic pregnant women reported using pressurized metered dose inhalers
(pMDIs) and dry powder inhalers (DPIs), respectively. Overall, wrong inhaler technique was observed in 47 (64.4%) subjects.
Among pMDI users, correct inhaler use was observed in only 26/73 (35.6%) of the patients, with lack of coordination between
inhalation and generation of the aerosol and failure to breathe out gently before using the inhaler, being the most common errors.
Among DPI users, 21 (51.2%) demonstrated correct inhaler use, with failure to perform a breath-hold for 10 seconds after inhaling
the powder and to exhale gently before using the inhaler being the most common errors. Significant associations between inhaler
technique and patient’s understanding of asthma medications and the kind of follow-up clinic (respiratory versus nonrespiratory
clinic) were found. No significant associations between inhaler technique and various maternal and fetal outcomes or asthma
control were found. In conclusion, improper inhalation technique is significantly prevalent in pregnant asthmatic women,
particularly among those being followed in nonspecialized respiratory clinics. +e lack of significant association between the
inhaler technique and asthma control (and hence maternal and fetal outcomes) may simply reflect the high prevalence of
uncontrolled asthma and significant contribution of other barriers to poor asthma control in the current patient’s cohort.
Multidisciplinary management of asthma during pregnancy with particular emphasis on patient’s education is imperative.