Author/Authors :
Falzarano, Gabriele Department of Orthopedics and Traumatology- Azienda Ospedaliera “Gaetano Rummo” Benevento, Italy , Medici, Antonio Department of Orthopedics and Traumatology- Azienda Ospedaliera “Gaetano Rummo” Benevento, Italy , Cioffi, Raffaele Department of Orthopedics and Traumatology- Azienda Ospedaliera “Gaetano Rummo” Benevento, Italy , Piscopo, Antonio Department of Orthopedics and Traumatology - Sacro Cuore di Ges`u Fatebenefratelli Hospital - Benevento, Italy , Grubor, Predrag Clinic of Traumatology - University Hospital Clinical Center Banja Luka - Banja Luka, Bosnia and Herzegovina , Rollo, Giuseppe Department of Orthopedics and Traumatology - Vito Fazzi Hospital - Lecce, Italy , Pipola, Valerio Rizzoli Orthopedic Institute - University of Bologna - Bologna, Italy , Bisaccia, Michele Division of Orthopedics and Trauma Surgery - University of Perugia - S. Maria della Misericordia Hospital - Perugia, Italy , Caraffa, Auro Division of Orthopedics and Trauma Surgery - University of Perugia - S. Maria della Misericordia Hospital - Perugia, Italy , Meccariello, Luigi Division of Orthopedics and Trauma Surgery - University of Perugia - S. Maria della Misericordia Hospital - Perugia, Italy , Barron, Elizabeth Mary Central Michigan University - Mount Pleasant - MI, USA , Nobile, Francesco Department of Orthopedics and Traumatology - Hospital “Santa Maria alla Gruccia” - Montevarchi - Arezzo, Italy
Abstract :
Orthopedic implants have become essential components of modern medicine. The risk of infection of total hip arthroplasty (THA)is 1.5%−2%. Are the C-reactive protein (CRP), the erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) good markersfor THA infection screenings? From February 2009 to December 2012 at our Department of Orthopedics and Traumatology,1248 patients were treated with THA. No prosthesis was cemented. All patients received antibiotic prophylaxis. All patients weredischarged approximately 7.4 days after surgery with this clinical and radiographic follow-up program at 15 days and 1, 3, 6, 12, 24,and 36 months after surgery. Blood samples to determine ESR, CRP, and PCT values were taken at 1 hour before surgery and 15 daysand 1, 3, 6, 12, 24, and 36 months after surgery. During follow-ups there were 22 cases of THA infections; according the Widmerclassification, infections are hematogenous ones in 16 cases, late chronic ones in 5 cases, and early postoperative ones in 1 case. Inall cases the three markers were considered positive; in 6 cases there were no radiological signs of septic loosening. ESR, CRP, andPCT proved to have a greater diagnostic accuracy than X-rays in predicting late chronic and early postoperative infections. Thesemarkers are valuable support for the surgeon in monitoring the prosthetic implant lifespan
Keywords :
Common Inflammatory Markers , Long-Term Screening , Total Hip Arthroprosthesis Infections , Experience
