Author/Authors :
Eliseeva, T. I. Department of Hospital Pediatrics and Department of ENT Diseases - Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia , Krasilnikova, S. V. Department of Hospital Pediatrics and Department of ENT Diseases - Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia , Geppe, N. A. Department of Children Diseases - I.M. Sechenov First Moscow State Medical University, Moscow, Russia , Babaev, S. Yu. Department of Hospital Pediatrics and Department of ENT Diseases - Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia , Tush, E. V. Department of Hospital Pediatrics and Department of ENT Diseases - Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia , Khaletskaya, O. V. Department of Hospital Pediatrics and Department of ENT Diseases - Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia , Ovsyannikov, D. Yu. Department of Pediatrics - Medical Institute - Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia , Balabolkin, I. I. Department of Pulmonology and Allergology - National Scientific and Practical Centre of Children’s Health, Moscow, Russia , Ignatov, S. K. Department of Chemistry - Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia , Kubysheva, N. I. Medical Informatics Research Laboratory of the Higher School of Information Technologies and Information Systems - Kazan Federal University, Kazan, Republic of Tatarstan, Russia
Abstract :
Allergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial
asthma (BA) frequently accompanied with nasal obstructive diseases (NOD). In order to establish the effect of NOD on correlations between nasal and synonasal symptoms with clinical assessments of asthma control, 82 children, 9.8 [8.9; 10.7] years old,
with atopic BA were assessed using ACQ-5 for the BA control level, TNSS for nasal symptoms, and SNOT-20 for synonasal quality
of life in combination with rhinovideoendoscopy for NOD. All patients had AR/ARS; in 76.3% (63/82) of children, UAP had
a multimorbid character with the presence of NOD. Significant correlations were found between ACQ-5 and TNSS
(R = 0.40, p < 0.0001) and ACQ-5 and SNOT-20 (R = 0.42, p < 0.0001). Correlations between TNSS/ACQ-5 and SNOT20/ACQ-5 were higher in patients who do not have a combination of AR/ARS with NOD (R = 0.67, p = 0.0012;
R = 0.50, p = 0.022, resp.) than in patients who have AR/ARS combined with NOD (R = 0.30, p = 0.015; R = 0.26, p = 0.04,
resp.). (us, the association of BA control level with the expression of nasal and synonasal symptoms is higher in children who do
not have multimorbid UAP.
