Author/Authors :
Shi, Yu Department of Radiotherapy - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China , Yang, Jianxin Department of General Surgery - Qidong People’s Hospital - Qidong Liver Cancer Institute, Nantong, Jiangsu, China , Yao, Ninghua Department of Radiotherapy - Affiliated Hospital of Nantong University, Nantong, Jiangsu, China , Shao, Minghai Department of Radiotherapy - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China , Ding, Wenxiu Department of Radiotherapy - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China , Jiang, Wanrong Department of Radiotherapy - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China , Sun, Xinchen Department of Radiotherapy - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China
Abstract :
Background. +e aim was to investigate the potential factors related with overall survival of oligometastatic non-small-cell lung
cancer (NSCLC) patients. Methods. A literature search was conducted in databases including PubMed, Embase, and Cochrane
library up to March 2017. The hazard radio (HR) as well as the corresponding 95% confidence interval (CI) were calculated, and all
the statistics analysis was performed by the R 3.12. Heterogeneity was analyzed using I-squared and Cochran Q tests. Furthermore,
sensitivity analysis was performed to evaluate the stability of results. Results. In total, 6 articles were included in the meta-analysis.
Nodal status was significantly correlated with the overall survival rate of NSCLC oligometastatic patients (HR: 1.69, 95% CI:
1.23–2.32, Z = 3.20, P = 0.001). No significant relationship was found between overall survival rate of NSCLC oligometastatic
patients and the indicators including sex, stage, smoker, age, and histology. Notably, sensitivity analysis on data evaluating
relationship between patients survival and the stage and histology showed that results were reversed after removing one of the
studies. Conclusions. Nodal status might be associated with the overall survival of oligometastatic NSCLC patients.
