Author/Authors :
Wang, Li Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Ai, Tao Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Luo, Ronghua Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Fan, Yinghong Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Liao, Huiling Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Xia, Wanmin Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Xie, Cheng Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Duan, Yaping Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China , Liu, Yanru Pediatric Respiratory Medicine Department - Chengdu Women’s and Children’s Central Hospital - School of Medicine - University of Electronic Science and Technology of China, Chengdu, China
Abstract :
Objective. To evaluate the efficiency of sublingual immunotherapy with Dermatophagoides Farinae Drops in children with single
and multiple respiratory allergic diseases. Methods. Seventy-one children with allergic respiratory diseases who had been treated
with Dermatophagoides Farinae Drops for one year or more were divided into a single allergic group (12 cases) and multiple
allergic group (59 cases). (e rhinitis score, daytime and night symptom score of asthma, VAS score, drug score, pulmonary
function, and FeNO level before and after treatment were evaluated and compared between the two groups. Results. (e rhinitis
score, night symptom score, VAS score, and drug score in the single allergic group after treatment were significantly lower than
those before treatment (p < 0.05), but there was no significant difference in the daytime symptom score before and after treatment
(p > 0.05). (e rhinitis score, VAS score, and drug score in the multiple allergic group after treatment were significantly lower than
those before treatment (p < 0.05), but there was no significant difference in the scores of daytime symptoms and nighttime
symptoms before and after treatment (p > 0.05). In both the single allergic group and multiple allergic group, the pulmonary
function indexes of the patients were significantly improved after treatment, and the FeNO after treatment was significantly lower
than that before treatment (p < 0.05). (ere was no significant difference in scores, pulmonary function, and FeNO between the
two groups (p > 0.05). Conclusion. Sublingual specific immunotherapy is effective in treating multiple and single allergic respiratory diseases in children.
Keywords :
Sublingual Duster , Mite Drops , Exhaled Nitric Oxide , Single Allergic , Respiratory Diseases
