Author/Authors :
Lorenzo, Giorgio Di Chair of Psychiatry - Department of Systems Medicine - University of Rome Tor Vergata - Rome, Italy , Rossi, Rodolfo Chair of Psychiatry - Department of Systems Medicine - University of Rome Tor Vergata - Rome, Italy , Niolu, Cinzia Chair of Psychiatry - Department of Systems Medicine - University of Rome Tor Vergata - Rome, Italy , Siracusano, Alberto Chair of Psychiatry - Department of Systems Medicine - University of Rome Tor Vergata - Rome, Italy , Rossi, Alessandro Department of Applied Clinical Sciences and Biotechnologies - University of L’Aquila - Via Vetoio - L’Aquila, Italy
Abstract :
Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between PosttraumaticStress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based onantidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors(SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes fornonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report oncomorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological andpharmacological aspects of the disorders are discussed
Keywords :
A Case of Comorbid PTSD , Posttraumatic OCD Treated , Sertraline-Aripiprazole Augmentation , OCD-PTSD , SGA
