Gastaut-Geschwind Syndrome, Faciobrachial Dystonic Seizure,and Autoimmune Limbic Encephalitis

Here we report a case of a 55-year-old male who had presented with recent falls and behavioral changes, including a heightenedreligious preoccupation, hypergraphia, and paranoid ideations. He was initially treated for psychosis but soon exhibited absence-like seizures, which were consistent with faciobrachial dystonic seizures. Workup for underlying infectious, immunodeficiency,and autoimmune causes revealed antibodies towards the leucine-rich glioma inactivated subunit of the voltage-gated potassiumcomplex. The patient was treated with steroids and intravenous immune globulin with symptomatic relief. In retrospect, the patientmet criteria for Gastaut-Geschwind (GG) syndrome, with notable features of hypergraphia and hyperreligiosity. This case illustrateshow the GG syndromal pattern contributes to the suspicion of autoimmune limbic encephalitis and may expedite diagnosis andprevent the accumulation of disability