A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)

Objective. To investigate the epidemiologic and etiologic factors, clinical features, therapeutic regimen, and prognosis of crayfshrelated rhabdomyolysis (Haf disease). Methods. Retrospectively analyzed the clinical data of 29 patients with crayfsh-related rhabdomyolysis (Haf disease) from July to August 2016, summarized the clinical characteristics, and evaluated the prognosis. Results. Clinical data of a total of 29 cases of Haf disease were retrospectively analyzed. The disease onset occurred after consumption of cooked crayfsh with the incubation period ranging from 1 h to 48 h. Tere were no gender diferences and signifcantly elevated CK in the duration with peak value of 41575.0U/L; the median value was 2445.0U/L (range: from 1187.0 U/L to 4722.0 U/L) and there was coincident elevated CK-MB. Tere was also no hepatorenal damage and transient urinalysis was abnormal. The most common presenting symptoms were myalgia (100%), weakness and numbness (51.7%), chest tightness and chest pain (41.4%), back pain (41.4%), and extremities pain (37.9%). All the patients recovered and no patients died. Conclusions. Crayfsh-related rhabdomyolysis (Haf disease) is a kind of a case or cluster of patients present with severe myalgia or weakness of unknown etiology and mechanism disease; however, the clinical signs and symptoms are relatively mild with favorable outcome.