Author/Authors :
Yan, Zhang Department of Geriatric Psychiatry - The Third People’s Hospital of Fuyang, Hangzhou, China , Yingjie, Zhang Department of Addiction Medicine - An Ding Hospital - Capital Medical University, Beijing, China , Na, An Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China , Qi, Qiu Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China , Wei, Li Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China , Wenzheng, Wang Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China , Lin, Sun Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China , Shifu, Xiao Alzheimer’s Disease and Related Disorders Center - Department of Geriatric Psychiatry, Shanghai Mental Health Center - Shanghai Jiao Tong University School of Medicine, Shanghai, China
Abstract :
Aim. To investigate the effects of light-to-moderate drinking on the cognitive function of the elderly in a large elderly community
cohort. Although heavy drinking is linked with impaired brain functions, the effects of light-to-moderate drinking on the cognitive
function of the elderly are still controversial. Methods. A total of 1469 nondemented elderly men from 15 research centers in 8 cities
and provinces were included and divided into two groups: drinking (531 subjects) and nondrinking (938 subjects). Cognitive
functions were assessed by the Beijing version of the Montreal Cognitive Assessment (MoCA) at baseline and one-year followup. Results. There was no difference in total cognitive scores between the light-to-moderate drinking and nondrinking groups at
baseline and follow-up. Nonalcohol users performed better naming and abstraction function at baseline and better naming
function at follow-up. There was no difference in cognitive performance decline and new-onset dementia rates at follow-up.
Conclusions. Light-to-moderate alcohol consumption had no significant impact on the overall cognitive function and the risk of
dementia in elderly men.
Keywords :
Light-to-Moderate , Alcohol Consumption , Cognitive Function , Community Nondemented Male Elderly
