Author/Authors :
Cohen, David Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Cravero, Cora Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Guinchat, Vincent Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Xavier, Jean Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Meunier, Camille Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Diaz, Lautaro Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Consoli, Angèle Department of Child and Adolescent Psychiatry - Reference Centre for Rare Psychiatric Diseases - AP-HP,Groupe Hospitalier Piti ́e-Salpˆetri`ere - Universit ́e Pierre et Marie Curie - 47-83 Bd de l’Hˆopital - Paris, France , Mignot, Cyril Department of Pediatric Neurology - AP-HP - Hˆopital Armand-Trousseau - Avenue du Dr. Arnold Netter - Paris, France , Doummar, Diane Department of Pediatric Neurology - AP-HP - Hˆopital Armand-Trousseau - Avenue du Dr. Arnold Netter - Paris, France , Chantot-Bastaraud, Sandra DepartmentofGenetics - DivisionofChromosomalGenetics - AP-HP - Hˆopital Armand-Trousseau- Paris, France
Abstract :
We report the case of a young boy with nonverbal autism and intellectual disability, with a rare de novo 1q21.3 microdeletion. Thepatient had early and extreme self-injurious behaviours that led to blindness, complicated by severe developmental regression.A significant reduction in the self-injurious behaviours and the recovery of developmental dynamics were attained in amultidisciplinary neurodevelopmental inpatient unit. Improvement was obtained after managing all causes of somatic pains, usingopiate blockers and stabilizing the patient’s mood. We offered both sensorimotor developmental approach with therapeutic bodywrap and specific psychoeducation adapted to his blindness condition for improving his communication abilities.
Keywords :
Management , Severe Developmental Regression , Autistic Child , 1q21.3 Microdeletion , Self-Injurious Blindness
