Alagille Syndrome: A Case Report HighlightingDysmorphic Facies, Chronic Illness, and Depression

Alagille syndrome is a rare multisystem disorder affecting the liver, heart, vertebrae, eyes, and face. Alagille syndrome sharesmultiple phenotypic variants of other congenital or chronic childhood illnesses such as DiGeorge syndrome, Down syndrome,spina bifida, type 1 diabetes mellitus, and cystic fibrosis. All of these chronic illnesses have well-established links to psychiatricconditions. There are few community resources for Alagille patients, as it is an extremely rare condition. Despite the overlapwith other chronic childhood illnesses, the psychiatric manifestations of Alagille syndrome have not been previously discussed inliterature. The current study is a case report of a twelve-year-old female hospitalized in our pediatric psychiatric hospital for suicidalideation with intent and plan. The patient had major depressive disorder, anxiety, other specified feeding and eating disorder, andattention-deficit/hyperactive disorder