Author/Authors :
Ibrahim, Toni Department of Cardiology - Bekaa Hospital, Zahle, Lebanon , El Karak, Fady Department of Cardiology - Bekaa Hospital, Zahle, Lebanon , Araji, Assem Department of Cardiology - Bekaa Hospital, Zahle, Lebanon , El Rassy, Elie Department of Hematology - Hotel-Dieu de France University Hospital - Faculty of Medicine - Saint Joseph University, Beirut, Lebanon
Abstract :
A 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty.
He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and
a combination of antihistamine H1 and antihistamine H2 for symptomatic management. The thrombocytopenia spontaneously
resolved uneventfully in 48 hours thereafter. This case report suggests a possible association between TIT and inflammatory bowel
disease. Therefore, strict monitoring of the platelet count is required in patients who develop allergic reactions to tirofiban.
