Title of article :
Unique Presentation of Rosai-Dorfman Disease as ConcomitantAppendiceal and Rectal Masses with IgG4-Positive Plasma CellsDiagnosed by Core Needle Biopsy
Author/Authors :
Makramalla, Abouelmagd University of Cincinnati Medical Center, USA , Poldemann, Jenna J. University of Cincinnati Medical Center, USA , Hinrichs, Benjamin H. University of Cincinnati Medical Center, USA
Abstract :
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare non-Langerhans cell histiocytosis.We report a case of a 69-year-old male with concurrent appendiceal and rectal masses who underwent CT-guided percutaneousbiopsy. Histopathology confirmed a diagnosis of RDD with IgG4-positive plasma cells. It is believed to be a subset of RDD thatshares similar features with IgG4-related disease suggesting some overlap of the two diseases. Because gastrointestinal RDDaccounts for less than 1% of extranodal disease, it is important to recognize this entity in order to guide management. Wereview the presentation, diagnosis, and treatment of gastrointestinal RDD and discuss the possible overlap with IgG4-relateddisease.
Keywords :
Unique Presentation , Rosai-Dorfman Disease , Concomitant Appendiceal , Rectal Masses , IgG4-Positive Plasma Cells Diagnosed , Core Needle Biopsy , RDD
Journal title :
Case Reports in Oncological Medicine
